Incubator Accessories
Diagnostic Biosystems CYTOKERATIN CAM52 Cytokeratin (CAM5.2)
Anti-Cytokeratin (CAM 5.2) reagent has a primary reactivity with human keratin proteins that correspond to Moll’s peptides #7 and #8, Mr 48 and 52 kilodaltons (kd), respectively. Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not onstratified squamous epithelium. Anti-Cytokeratin (CAM 5.2) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (CAM 5.2) might not react with some squamous cell carcinomas.
Diagnostic Biosystems CD138 CD138 (EP201)
CD138, also known as Syndecan-1, is a member of the transmembrane heparan sulfate proteoglycan family, acts as an extracellular matrix receptor and is involved in many cellular functions, including cell-cell adhesion and cell-matrix adhesion. CD138 expression is found in both hematopoietic and non-hematopoietic cells. In the hematopoietic system, CD138 labels plasma cells. It is an excellent marker for plasmacytic differentiation within the spectrum of hematologic malignancy. Among non-hematolymphoid cells, CD138 reactivity is observed in many types of epithelial cells and stoma cells in both normal and tumor tissues.
Diagnostic Biosystems CD8 T-CELL CD8 (SP16)
This antibody recognizes the CD8. The CD8 molecule consists of two chains, α and β, which are expressed as a disulphide-linked α/β heterodimer or as an α/α homodimer on T cell subset, thymocytes and NK cells. The majority of CD8+ T cells express CD8 as α/β heterodimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 α chain (but not β chain).
Diagnostic Biosystems SOX10 SOX10 (Melanoma Marker)
SOX10 is widely expressed in normal human tissues including melanocytes and breast tissue. SOX10 is also an important marker in malignant tumors such as melanoma, breast carcinoma, gliomas, and benign tumors such as schwannomas.SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes and myoepithelial cells ofsalivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.
Diagnostic Biosystems GFAP Glial Fibrillary Acidic Protein, GFAP
This antibody reacts with human GFAP. In the central nervous system, this antibody stains astrocytes and some groups of ependymal cells. However, in the peripheral nervous system, it stains Schwann cells, satellite cells and enteric glial cells.
Diagnostic Biosystems HELIOCOBACTER PYLORI Heliocobacter pylori
This antibody reacts with the whole H. pylori. The antibody stains the bacteria present on the surface of the epithelium or in the cytoplasm of the epithelial cells. H. pylori is known to cause peptic ulcer and chronic gastritis in humans.
Diagnostic Biosystems P16 p16
P16 is a mitotic inhibitor protein. It competes with D-type cyclins to bind to cdk4 and cdk6. It acts as tumor suppressor and inhibits the progression of cells through the G1 phase of the cell cycle.
Diagnostic Biosystems C1Q-FITC C1q Complement-FITC
This antibody reacts with the human C1q complement. Traces of contaminating antibodies have been removed by solid phase absorption with human plasma proteins. This antibody is well suited for tissue section staining but may also be used for other applications.
Diagnostic Biosystems THYROGLOBULIN Thyroglobulin (1D4)
This antibody recognizes thyroglobulin in hyperplastic and neoplastic thyroid. Thyroglobulin is a protein of 670 kDa consisting of two identical subunits. Thyroglobulin is synthesized by the follicular epithelial cells of the thyroid.
Diagnostic Biosystems PTAH PTAH
The PTAH Stain Kit is intended for use in the histological visualization of collagen, striated muscle, glial fibers and collagen without using Zenker’s Fixative containing Mercuric Chloride. This kit may be used on formalin-fixed, paraffin-embedded or frozen sections.
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